Mechanisms of specific immunological unresponsiveness to bacterial lipopolysaccharides
نویسندگان
چکیده
منابع مشابه
Alloantigen-induced specific immunological unresponsiveness.
When the immune system encounters alloantigen it can respond in any one of a number of different ways. The choice that is made will take into account factors such as where, when and how the contact with the alloantigen takes place, as well as the environmental conditions that prevail at the time the alloantigen is encountered. Alloantigen administration before transplantation either alone or in...
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Alloantigen administration before transplantation, either alone or in combination with therapeutic agents that modulate the functional activity of the responding leukocytes, can be a powerful way of inducing specific unresponsiveness to alloantigens in vivo. In theory, any cell expressing one or more donor alloantigens has the ability to modulate the subsequent immune response to an allograft e...
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Immunologic unresponsiveness (paralysis) to pneumococcal polysaccharide, first described in detail by Felton (1-5), represents a simple, easily manipulated model for the study of the unresponsive state. I t is now generally agreed that paralysis to polysaccharides and unresponsiveness to protein antigens are both expressions of the same basic biologic mechanisms (6). Current evidence supports t...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 1987
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.55.12.3093-3102.1987